The drive from Alice to McAllen is a 150-kilometer trip that takes you south into the Rio Grande Valley. You will primarily use US-281 South, which transitions into I-69C. This route is the main corridor for travel between the Alice area and the major urban centers of the Valley. The drive typically takes about 1 hour and 30 minutes. You will pass through agricultural lands and small towns before reaching the bustling McAllen metropolitan area.
Total Distance: 150 km driving distance; 135 km straight-line air distance.
I-69C is a major highway; expect heavy traffic near McAllen.
Winter, when the weather is pleasant and the Valley is a popular destination.