The journey from Alice to San Antonio covers 220 kilometers, primarily via US-281 North. This route takes you through the heart of the South Texas brush country. You will pass through several small towns, including George West and Pleasanton, before arriving in the vibrant city of San Antonio. The drive typically takes about 2 hours and 30 minutes. It is a popular route for those heading to the city for business or tourism.
Total Distance: 220 km driving distance; 195 km straight-line air distance.
US-281 is a major highway; expect heavy traffic as you approach the San Antonio loop.
Spring or Fall, when the weather is mild for exploring the River Walk.