The journey from Allentown to Indianapolis is approximately 600 miles, taking about 9.5 hours via I-70 West. This route takes you across Pennsylvania, Ohio, and into Indiana. It is a major cross-country corridor, offering many service plazas and towns for rest. Plan for a long day of driving or consider an overnight stop.
Total Distance: 965 km driving distance; 800 km straight-line air distance.
I-70 is very direct but can have heavy truck traffic.
Summer or early fall for the best road conditions.