The drive from Amarillo to Memphis is a straightforward 1,100-kilometer journey primarily along Interstate 40 East. You will traverse the entire width of Oklahoma and Arkansas before entering Tennessee. This route takes you through major cities like Oklahoma City and Little Rock. Expect a total driving time of approximately 11 hours without major stops. It is a classic American road trip route through the heart of the South.
Total Distance: 1,100 km driving, 1,050 km air distance.
Traffic in Little Rock can be heavy during rush hour.
Spring or Fall to avoid extreme heat in the South.