How long is the drive to Memphis?

It takes approximately 16 hours depending on traffic.

Are there tolls on this route?

Some sections of the Ohio Turnpike may be involved.

Is it better to fly or drive?

Driving is usually more convenient as direct flights are limited from Buffalo.

What is the best route?

Take I-90 W to I-71 S, then merge onto I-40 W.

Are there many rest stops?

Yes, the interstate system has frequent service plazas.

Amherst

Memphis

Driving

Amherst to Memphis

Updated: 28 May 2026

The drive from Amherst to Memphis is approximately 1,050 miles. The most efficient route takes you through Ohio, Kentucky, and into Tennessee via I-71 and I-40. Expect a driving time of about 16 hours. This route is a great way to see the heart of the United States. Plan for at least one overnight stop to break up the long journey.

Total Distance: 1,690 km driving distance, 1,400 km air distance.

Fastest Way

Driving is the most practical; flights from Buffalo to Memphis often require a connection.

Cheapest Way

Driving is the most cost-effective way to reach Memphis from Amherst.

Compare Amherst to Memphis Routes

Driving

Direct

Duration

16 hours

Avg Price

$180-$250 in fuel

Operator

Personal Vehicle

Route

I-90 W to I-71 S to I-40 W.

Plan for an overnight stop in a city like Louisville or Nashville.

Travel Tips

Route Planning
Use a GPS app to monitor construction delays on I-40 near Memphis.
Rest Stops
The interstate system offers well-maintained service plazas with food and fuel.
Traffic
Avoid passing through major cities during rush hour to save time.
Fueling
Gas prices are often competitive in the Midwest, so plan your fill-ups accordingly.
Accommodation
Book hotels in the downtown area early if visiting during major events.

Safety Tips

Fatigue Management
Take a 15-minute break every 3 hours to stay alert on the highway.
Weather Monitoring
Check for severe weather warnings in the South, especially during spring.
Vehicle Check
Ensure your tire pressure and oil levels are optimal before starting a 1,050-mile trip.
Emergency Contacts
Save the highway patrol numbers for New York, Ohio, Kentucky, and Tennessee.