Driving
Appleton to Des Moines
Updated: 28 May 2026
The drive from Appleton to Des Moines is a 380-mile journey across Wisconsin, Minnesota, and Iowa. You will take I-90 West to Albert Lea, then transition to I-35 South toward Des Moines. The trip takes approximately 6 hours, passing through diverse landscapes from the forests of Wisconsin to the plains of Iowa. This is a major cross-state route that requires careful planning for fuel and rest stops. It is a popular path for those traveling between the Midwest's major urban centers.
Total Distance: 610 km driving distance; 520 km straight-line air distance.
Fastest Way
Driving is the fastest way, taking about 6 hours.
Cheapest Way
Driving your own vehicle is the most cost-effective method.
Compare Appleton to Des Moines Routes
Driving
Direct
Duration
6 hours
Avg Price
$60-$80 in fuel
Operator
Personal Vehicle
Route
I-90 West to I-35 South.
Albert Lea is a great place to stop for a meal and fuel.
Travel Tips
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TrafficTraffic is generally light, but watch for congestion near Des Moines.
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FuelingPlan your fuel stops in advance, especially in rural stretches of Minnesota and Iowa.
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NavigationUse a GPS to ensure you make the correct turn onto I-35 in Albert Lea.
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Rest StopsThere are many well-maintained rest areas along I-90 and I-35.
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ParkingDes Moines has plenty of parking options in the downtown area.
Safety Tips
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Speed LimitsFollow speed limits strictly, especially in rural areas where enforcement is active.
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ConstructionCheck for road work on I-35 before you depart.
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VisibilityKeep your windshield clean for better visibility during long-distance driving.
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Emergency KitAlways carry an emergency kit in your vehicle for long-distance trips.
People Also Ask
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Is there a train to Des Moines?No, there is no direct passenger rail service to Des Moines from Appleton.
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How long is the drive?The drive takes about 6 hours.
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What is the best route?I-90 West to I-35 South is the most direct route.
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Are there tolls?No, there are no tolls on this route.
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Is it a difficult drive?It is a long but straightforward highway drive.
Quick Info
- From Appleton, Wisconsin, United States
- To Des Moines, Iowa, United States
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Modes
Best Time to Travel
Late spring or early autumn for pleasant driving weather.
Things to Do in Des Moines
1
State Capitol
The Iowa State Capitol is a stunning building with a gold-leaf dome. It offers tours and beautiful grounds to explore.
2
Greater Des Moines Botanical Garden
This garden features a unique geodesic dome and diverse plant collections. It is a beautiful place to visit year-round.
3
Pappajohn Sculpture Park
Located in downtown, this park features world-class sculptures in an open-air setting. It is free and accessible to everyone.
4
East Village
This historic neighborhood is filled with local shops, restaurants, and cafes. It is the perfect place to experience the local culture.
Tags
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I-90 to I-35 route
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Appleton to Des Moines distance
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Wisconsin to Iowa road trip
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