The drive from Beaufort to Greenville covers approximately 550 kilometers. You will travel west on US-70, then south on I-26 to reach the city of Greenville. Driving is the most practical mode of transport, as there is no direct public transit. Expect a travel time of roughly 6 hours, depending on traffic near the I-26 corridor. This route takes you through the heart of North Carolina and into the historic city of Greenville, South Carolina.
Total Distance: 550 km driving distance; 480 km straight-line air distance.
Monitor traffic reports for the I-26 corridor near the South Carolina border.
Spring or Autumn for mild weather and manageable traffic.