How long is the drive from Maryland to Buffalo?

It is about 8 to 9 hours of driving time.

What is the best route to Buffalo?

Taking I-81 and I-90 is the most direct and efficient route.

Are there tolls on the way to Buffalo?

Yes, there are tolls on the New York State Thruway.

What is the best time to visit Buffalo?

Spring and Fall offer the most comfortable weather.

Is Buffalo a walkable city?

The downtown area is walkable, but you will need a car for other parts of the city.

Berlin

Buffalo

Driving

Berlin to Buffalo

Updated: 30 May 2026

The drive from Berlin, Maryland to Buffalo, New York covers approximately 450 miles. You will travel north through Maryland, Pennsylvania, and into New York, primarily following I-81 and I-90. The journey takes about 8 to 9 hours, making it a manageable single day of driving. This route takes you through the scenic Appalachian Mountains and into the Great Lakes region.

Total Distance: Driving distance 750 km, straight-line air distance 600 km.

Fastest Way

Driving via I-81 and I-90 is the most efficient route, taking approximately 8 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective way to reach Buffalo.

Compare Berlin to Buffalo Routes

Driving

Direct

Duration

8 hours

Avg Price

80-120 USD in fuel

Operator

Personal Vehicle

Route

US-113 N to I-81 N to I-90 W through Scranton and Syracuse.

Be prepared for tolls on the New York State Thruway.

Travel Tips

Traffic
Avoid the I-90/I-190 interchange in Buffalo during rush hour.
Dining
Try the famous Buffalo wings at a local restaurant.
Parking
Use the public garages downtown; street parking is limited.
Walking
The downtown area is walkable, but the city is spread out.
Events
Check the calendar for events at the KeyBank Center.

Safety Tips

Long-Distance Driving
Take frequent breaks to avoid driver fatigue.
Weather
Be aware of heavy snow in the winter; Buffalo is known for lake-effect snow.
Night Driving
Avoid driving through the mountains at night if possible.
Emergency
Buffalo has excellent medical facilities.