The drive from Berlin, Maryland to Chicago, Illinois is a major cross-country journey of approximately 780 miles. You will travel west through Maryland, Pennsylvania, Ohio, and Indiana before reaching Illinois, primarily via I-70 and I-80. This trip is best completed over two days to ensure driver safety. Driving is the most practical mode for those who want to explore the Midwest. Expect a total driving time of about 13 to 14 hours.
Total Distance: 1,250 km driving distance; 1,050 km straight-line air distance.
Plan an overnight stop in a city like Pittsburgh, PA or Cleveland, OH.
Spring or Fall to enjoy the pleasant weather and avoid the harsh winter snow or summer heat.