Driving
Berlin to Syracuse
Updated: 30 May 2026
The drive from Berlin, Maryland to Syracuse, New York covers approximately 350 miles. You will travel north through Maryland, Pennsylvania, and into New York, primarily following I-81. The journey takes about 6 to 7 hours, making it a manageable single day of driving. This route takes you through the scenic Appalachian Mountains and into the heart of New York State.
Total Distance: Driving distance 550 km, straight-line air distance 450 km.
Fastest Way
Driving via I-81 is the most efficient route, taking approximately 6 hours.
Cheapest Way
Driving your own vehicle is the most cost-effective way to reach Syracuse.
Compare Berlin to Syracuse Routes
Driving
Direct
Duration
6 hours
Avg Price
60-100 USD in fuel
Operator
Personal Vehicle
Route
US-113 N to I-81 N through Scranton and Binghamton.
Be prepared for tolls on the New York State Thruway if you continue past Syracuse.
Travel Tips
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TrafficAvoid the I-81/I-690 interchange in downtown Syracuse during rush hour.
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DiningTry the local salt potatoes at a local restaurant.
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ParkingUse the public garages downtown; street parking is limited.
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WalkingThe downtown area is walkable, but the city is spread out.
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EventsCheck the calendar for events at the Oncenter.
Safety Tips
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Long-Distance DrivingTake frequent breaks to avoid driver fatigue.
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WeatherBe aware of heavy snow in the winter.
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Night DrivingAvoid driving through the mountains at night if possible.
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EmergencySyracuse has excellent medical facilities.
People Also Ask
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How long is the drive from Maryland to Syracuse?It is about 6 to 7 hours of driving time.
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What is the best route to Syracuse?Taking I-81 is the most direct and efficient route.
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Are there tolls on the way to Syracuse?There are no tolls on I-81, but there are tolls on the New York State Thruway if you continue past Syracuse.
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What is the best time to visit Syracuse?Spring and Fall offer the most comfortable weather.
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Is Syracuse a walkable city?The downtown area is walkable, but you will need a car for other parts of the city.
Quick Info
- From Berlin, Maryland, United States
- To Syracuse, New York, United States
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Modes
Best Time to Travel
May to June or September to October for pleasant temperatures.
Things to Do in Syracuse
1
Erie Canal Museum
Learn about the history of the Erie Canal in this fascinating museum.
2
Destiny USA
Explore this massive shopping and entertainment complex. It is a major destination.
3
Rosamond Gifford Zoo
Enjoy this beautiful zoo located in Burnet Park.
4
Onondaga Lake Park
Take a walk or bike ride along the beautiful lakefront.
Tags
Berlin MD to Syracuse NY
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