The journey from Biddeford to Framingham covers approximately 185 kilometers primarily via I-95 South and I-495 South. Driving is the most efficient method, typically taking two hours depending on traffic near the I-95/I-495 interchange. You can also utilize the Amtrak Downeaster from Saco to Boston North Station, followed by a transfer to the MBTA Commuter Rail. This route traverses the coastal plains of Maine into the suburban landscape of MetroWest Massachusetts. Expect heavy congestion during weekday rush hours near the I-95 corridor.
Total Distance: 185 km driving, 160 km air distance.
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Connecting
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Direct
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| Duration | 4 hours | 2 hours 10 mins |
| Avg Price | $35-$60 | $25-$40 in fuel |
| Operator | Amtrak and MBTA | Personal Vehicle |
| Route | Amtrak Downeaster to North Station, then MBTA Commuter Rail to Framingham. | I-95 S to I-495 S via exit 29B. |
| Tip | You must transfer between North Station and South Station in Boston. | Use the Mass Pike (I-90) if I-495 is congested near Marlborough. |
May through October for clear roads and pleasant weather.