The drive from Birmingham to Pensacola is a 400-kilometer trip that takes about 4 hours. You will head south on I-65 to I-10, then east into Florida. This is a popular route for those seeking the white sands of the Florida Panhandle. The drive is straightforward but can be busy during holiday weekends.
Total Distance: 400 km driving, 350 km air distance.
The I-65/I-10 interchange is well-marked; stay alert.
Late spring or early autumn for the best beach weather.