The journey from Bluffton to Jacksonville is a straightforward 170-kilometer drive south on I-95. You will cross the border from South Carolina into Georgia and then into Florida, a trip that typically takes 2 hours. This route is a major artery for East Coast travel, so expect heavy truck traffic. Jacksonville is a sprawling city, so plan your final destination within the city carefully to avoid unnecessary driving.
Total Distance: 170 km driving, 150 km air distance.
I-95 can be very busy; use cruise control for a smoother drive.
Late fall or early spring for comfortable temperatures and outdoor activities.