The drive from Bristol to Greenville is a 150-mile journey through the Blue Ridge Mountains. You will take I-26 East, with the trip taking approximately 2.5 hours. This route offers a beautiful drive through the mountains of Tennessee and North Carolina before reaching South Carolina.
Total Distance: 241 km driving distance, 190 km straight-line air distance.
I-26 is a winding mountain road; drive carefully.
Spring or Fall for the best scenery.