Is there a direct train?

No, you must transfer at Chicago Union Station.

How far is the drive?

It is approximately 1,520 kilometers.

What is the best airport?

St. Louis Lambert International Airport (STL) is the primary hub.

Yes, Greyhound operates routes from New York City to St. Louis.

Yes, I-80 and I-70 are major, well-maintained interstates.

Bronx

St. Louis

Train Flight

Bronx to St. Louis

Updated: 29 May 2026

The journey from the Bronx to St. Louis spans approximately 1,500 kilometers. You can fly from LaGuardia or JFK to St. Louis Lambert International Airport in about 3 hours. Alternatively, take the Amtrak Lake Shore Limited from Penn Station to Chicago, then transfer to the Lincoln Service. Driving via I-80 W and I-70 W takes roughly 16 hours of pure road time. This route crosses the Appalachian Mountains and the vast plains of the Midwest. Expect varied terrain and significant weather changes during the transition from the East Coast to the Mississippi River valley.

Total Distance: Driving distance 1,520 km, straight-line air distance 1,450 km.

Fastest Way

Flight from LaGuardia (LGA) to St. Louis (STL) with a connection, taking roughly 5 hours total.

Cheapest Way

Bus via Greyhound, typically $140, though it requires multiple transfers and long travel times.

Compare Bronx to St. Louis Routes

	Train Connecting	Flight Connecting
Duration	26 hours	3 hours 15 mins
Avg Price	$200 - $450	$180 - $350
Operator	Amtrak	American Airlines
Route	Penn Station to Chicago Union Station, then Lincoln Service to St. Louis.	LGA/JFK to STL via Chicago or Charlotte.
Tip	Upgrade to a Roomette for a comfortable overnight experience.	Book at least 3 weeks in advance to secure lower fares.

Travel Tips

Airport Transit
Use the MetroLink light rail to get from St. Louis Lambert Airport to downtown.
Packing
Pack layers as the Midwest experiences rapid temperature shifts.
Booking
Use aggregator sites to compare flight prices from LGA, JFK, and EWR.
Dining
Try the local St. Louis-style pizza with Provel cheese.
Connectivity
Download offline maps as cell service can be spotty in rural Pennsylvania.

Safety Tips

Urban Awareness
Stay in well-lit, populated areas when exploring downtown at night.
Driving Safety
Avoid driving through the Appalachian region during heavy winter snowstorms.
Public Transit
Keep your belongings secure while riding the MetroLink.
Emergency Prep
Carry a portable power bank for your phone during long train rides.