The most practical way to travel from Burlingame to Fresno is by driving via I-5 S and CA-99 S. The journey takes approximately 3 hours. Fresno is located in the heart of the Central Valley and serves as a gateway to Yosemite National Park. It is a major agricultural hub with a growing urban center.
Total Distance: 250 km driving distance; 220 km air distance.
CA-99 can be busy with truck traffic; drive defensively.
Spring or Fall for the most comfortable temperatures.