The drive from Cabot to St. Louis is approximately 600 kilometers and takes about 6 hours. You will head north on US-67 through Arkansas and Missouri, eventually connecting to I-55 into St. Louis. This is a long but straightforward drive. The route passes through various landscapes, from the Arkansas Delta to the rolling hills of Missouri.
Total Distance: 600 km driving distance; 520 km straight-line air distance.
Traffic in St. Louis can be heavy; plan accordingly.
Spring and Fall for the best outdoor weather.