Traveling from the coast at Cannon Beach to the high desert of Klamath Falls requires crossing the Cascade Range. The most efficient route involves taking US-26 and US-97 or I-5 to OR-58. You will transition from temperate rainforest to volcanic landscapes. The total distance is approximately 500 kilometers. Expect a drive time of 7 to 8 hours.
Total Distance: 500 km driving, 410 km air distance.
The stretch between Bend and Klamath Falls is scenic but remote.
June to August to avoid mountain pass snow closures.