The drive from Castaic to Chicago is a 2000-mile trip using the I-80 East. You will travel through the scenic landscapes of California, Nevada, Utah, Wyoming, Nebraska, and Iowa. Travel time is typically 30 hours, though it can vary based on traffic and weather. This route is a major connection between Southern California and the Midwest. It is a beautiful drive with significant mountain and plains scenery.
Total Distance: 3200 km driving distance; 2800 km straight-line air distance.
The I-80 through the mountains and plains is long and remote; check your fuel levels.
Summer and early Fall offer the best conditions for driving through the mountains.