The drive from Centreville to Prince Frederick involves crossing the Chesapeake Bay and heading south on US-301 and MD-4. The total distance is approximately 95 kilometers. This route takes you through suburban and rural areas. Expect a travel time of about one hour and forty-five minutes, depending on traffic on the bridge and the highways.
Total Distance: 95 km driving distance; 85 km straight-line air distance.
MD-4 can be very congested; check traffic before you leave.
Spring and Autumn are the most pleasant times for this drive.