Traveling from Chattanooga to Jacksonville covers roughly 750 kilometers. The most direct route is via I-75 S to I-10 E, taking about 7 to 8 hours. You will pass through Atlanta and Macon before heading toward the Florida border. This route is popular for those heading to the Atlantic coast. Driving is the most practical mode as there are no direct train or bus lines that offer a competitive time advantage.
Total Distance: 750 km driving distance; 680 km straight-line air distance.
Atlanta traffic is the biggest variable; try to pass through mid-day or late night.
Late spring or early autumn to avoid the peak summer humidity and hurricane season.