What is the best route?

I-22 West to I-55 North is the most direct path.

Is St. Louis safe for tourists?

Yes, the downtown and tourist areas are generally safe.

What is the best food to try?

St. Louis-style pizza is a local specialty.

Are there direct flights?

No, you would need to fly out of Atlanta for a direct flight.

Colbert

Saint Louis

Driving

Colbert to Saint Louis

Updated: 31 May 2026

The drive from Colbert to St. Louis is approximately 900 kilometers. You will head west on I-20 to Birmingham, then take I-22 to Memphis, and finally I-55 North into St. Louis. This route takes about 9 hours of driving time. You will pass through the heart of the South and the Mississippi River valley. It is a straightforward drive that connects the Atlantic side of the South to the Midwest.

Total Distance: 900 km driving, 800 km air distance.

Fastest Way

Driving is the fastest method, as there are no direct flights from local regional airports.

Cheapest Way

Driving your own car is the most cost-effective way to travel.

Compare Colbert to Saint Louis Routes

Driving

Direct

Duration

9 hours

Avg Price

$120 - $160 in fuel

Operator

Personal Vehicle

Route

I-20 W, I-22 W, I-55 N.

Stop in Memphis for a break.

Travel Tips

Dining
Try the local St. Louis-style pizza and toasted ravioli.
Walking
The downtown area is very walkable and features many historic buildings.
Riverfront
Take a walk along the riverfront for great views of the Gateway Arch.
Parking
Use the many public parking garages available downtown.
Events
Check the city calendar for events at Busch Stadium.

Safety Tips

Stay Alert
Be aware of your surroundings when walking downtown at night.
Weather
Missouri weather can change quickly; check the forecast before heading out.
Navigation
Use GPS to navigate the city's one-way streets.
Emergency
Keep your phone charged and have a list of local emergency contacts.