Traveling from Cusseta to St. Louis covers roughly 850 kilometers. The most direct driving route involves taking I-85 to I-65 North through Birmingham and Nashville, then transitioning to I-55 North. This journey takes you through the heart of the American South and into the Midwest. You will cross the Mississippi River as you enter St. Louis. The drive is scenic, passing through the rolling hills of Tennessee and the flat plains of Southern Illinois.
Total Distance: 850 km driving, 720 km air distance.
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Connecting
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Direct
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|---|---|---|
| Duration | 16 hours | 9 hours |
| Avg Price | $120 - $200 | $130 in fuel |
| Operator | Greyhound | Personal Vehicle |
| Route | Atlanta to St. Louis via Nashville | I-65 N to I-55 N |
| Tip | Expect a layover in Nashville or Memphis when taking the bus. | Stop in Nashville for a meal to break up the long drive. |
May or October to enjoy the Gateway Arch grounds without extreme summer heat.