The drive from Daytona Beach to Charleston is a straightforward 450 km journey primarily along I-95 North. You will pass through the coastal regions of Georgia, including Savannah, before entering South Carolina. The drive takes approximately 5 hours under normal traffic conditions. It is a popular route for those looking to experience the historic charm of the Lowcountry.
Total Distance: 450 km driving, 410 km air.
Stop in Savannah for lunch to break up the drive.
Spring (March-May) for mild weather and blooming gardens.