The trip from Deerfield Beach to Naples is a quick 110-mile journey across the Florida peninsula. The most efficient route is I-75 West, famously known as Alligator Alley, which cuts directly through the Everglades. This drive typically takes 2 hours. It is a unique experience that transitions from the bustling Atlantic coast to the serene, upscale Gulf Coast of Naples. Ensure your vehicle is fueled before entering the Everglades stretch.
Total Distance: 180 km driving, 160 km air distance.
There are limited services on Alligator Alley; fuel up before leaving.
Winter months for the best weather and access to outdoor activities.