The journey from Del Rio to Santa Fe covers approximately 1,100 km. Driving via US-277 N and I-25 N is the most direct route, taking about 12 hours. Santa Fe is known for its unique architecture, art galleries, and rich history. This route takes you through the beautiful landscapes of West Texas and New Mexico.
Total Distance: 1,100 km driving, 950 km air distance.
The drive through the high desert is scenic, but watch for wildlife on the road.
Spring and fall offer the most pleasant weather for visiting Santa Fe.