There is no regular, scheduled bus service between these two cities.

How long is the drive?

The drive takes about 12 hours.

What is the best route?

Taking US-281 to I-94 to US-83 to I-80 to I-25 is the most efficient path.

No, there are no toll roads on this route.

Yes, it is a standard highway drive, though winter weather requires caution.

Devils Lake

Denver

Driving

Devils Lake to Denver

Updated: 29 May 2026

The drive from Devils Lake to Denver is a 800-mile trip that takes you south through North Dakota, Nebraska, and into Colorado. You will travel south on US-281 to Jamestown, then west on I-94 to Bismarck, south on US-83 to I-80, and finally south on I-25 to Denver. The drive typically takes about 12 hours. This route connects the rural lake region to the major metropolitan area of Denver.

Total Distance: 1,290 km driving distance; 1,150 km straight-line air distance.

Fastest Way

Driving via US-281, I-94, US-83, I-80, and I-25 is the fastest and only direct route.

Cheapest Way

Driving your own vehicle is the most practical and affordable option.

Compare Devils Lake to Denver Routes

Driving

Direct

Duration

12 hours

Avg Price

$120-$160 in fuel

Operator

Personal Vehicle

Route

US-281 S to I-94 W to US-83 S to I-80 W to I-25 S.

Expect heavy traffic in the Denver area, especially during rush hour.

Travel Tips

Speed Limits
Be careful to slow down when entering the small towns along the route.
Weather
Winter storms can make I-25 and I-80 treacherous; check the NDDOT, SDDOT, NeDOT, and CDOT websites before departing.
Fueling
There are many fuel stations along the route, especially in larger cities like Bismarck and Cheyenne.
Traffic
Expect heavy traffic when entering the Denver metropolitan area, especially during rush hour.
Navigation
The route is well-marked, but keep a GPS device or map handy for the transition between highways.

Safety Tips

Winter Driving
Always carry a winter emergency kit, as blowing snow can reduce visibility to zero.
Wildlife
Deer and elk are frequently seen near the highway; stay alert at all times.
Fatigue
Take regular breaks to stay alert on this long drive.
Visibility
Use your headlights during the day if conditions are overcast or snowy.