There are no direct buses; you would need to use regional transit with multiple transfers.

How long is the drive?

It takes about 4 hours under normal conditions.

What is the best route?

US-52 to I-35 is the most direct and reliable route.

No, there is no direct train service to Minneapolis.

Is it a difficult drive?

No, it is a straightforward drive through the Midwest.

Dubuque

Minneapolis

Driving

Dubuque to Minneapolis

Updated: 31 May 2026

The drive from Dubuque to Minneapolis covers approximately 350 kilometers. You will head north on US-52, then transition to I-35 to reach the city. This route takes you through the rolling hills and agricultural landscape of the Midwest. Minneapolis is a major city known for its vibrant downtown, beautiful lakes, and rich cultural history. Expect moderate traffic near the city center.

Total Distance: 350 km driving distance; 300 km straight-line air distance.

Fastest Way

Driving via US-52 and I-35 is the fastest route, taking about 4 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective way to reach Minneapolis.

Compare Dubuque to Minneapolis Routes

Driving

Direct

Duration

4 hours

Avg Price

$50 - $75 in fuel

Operator

Personal Vehicle

Route

US-52 N to I-35 N into Minneapolis.

Be prepared for beautiful agricultural landscapes.

Travel Tips

Traffic
Avoid the city center during rush hours to save significant time.
Weather
Minnesota can be cold in the winter; bring warm clothing.
Parking
Parking in Minneapolis can be difficult; look for city-owned lots.
Navigation
Use a GPS to navigate the city streets.
Dining
Try the local restaurants that highlight the city's diverse culinary scene.

Safety Tips

Driver Alertness
The long, straight stretches of the Midwest can be hypnotic; stay focused.
Emergency Kit
Keep water and snacks in your car for the long stretches between major towns.
Vehicle Maintenance
Check your oil and coolant levels before embarking on this 350 km trip.
Road Conditions
Check for construction updates on I-35 before you depart.