Eden Prairie
Eden Prairie
St. Louis
St. Louis
Driving

Eden Prairie to St. Louis

Updated: 29 May 2026

The drive from Eden Prairie to St. Louis covers approximately 500 miles. You will primarily travel south on I-35 before connecting to I-70 East. The journey takes roughly 8 hours of driving time depending on traffic in Des Moines. This route traverses the heart of the American Midwest through Iowa and Missouri. It is a straightforward drive suitable for a single-day trip.

Total Distance: Driving distance 800 km; Air distance 680 km.
Fastest Way
Driving via I-35 and I-70 is the fastest, taking 8 hours.
Cheapest Way
Driving your own vehicle is the most cost-effective method for groups.
Compare Eden Prairie to St. Louis Routes
Driving
Direct
Duration
8 hours
Avg Price
$80 - $120 (fuel)
Operator
Personal Vehicle
Route
I-35 S to I-80 E to I-70 E.

Stop in Des Moines for a quick lunch break to break up the drive.

Travel Tips
  • Traffic
    Avoid downtown St. Louis during morning and evening rush hours.
  • Parking
    Use parking apps to find affordable garages near the Arch.
  • Route
    Check for construction on I-70 near the Missouri border before departing.
  • Rest Stops
    Iowa has excellent rest areas along I-35 with clean facilities.
  • Dining
    Try St. Louis-style pizza and toasted ravioli at local eateries.
Safety Tips
  • Weather
    Be prepared for sudden thunderstorms in the Midwest during summer.
  • Road Conditions
    Check winter road reports if traveling between November and March.
  • Vehicle Check
    Ensure your tires and fluids are checked before a long highway drive.
  • Emergency
    Keep a roadside emergency kit in your trunk at all times.
People Also Ask
  • Is there a train?
    Amtrak offers service, but it requires a connection in Chicago.
  • How long is the drive?
    Approximately 8 hours of pure driving time.
  • Are there tolls?
    No major tolls on this specific interstate route.
  • Best place to stop?
    Des Moines, Iowa is the perfect midpoint for a break.
  • Is it safe?
    Yes, the route is well-traveled and safe for families.
Quick Info
  • From Eden Prairie, Minnesota, United States
  • To St. Louis, Missouri, United States
  • Modes
Best Time to Travel

September to October for mild temperatures and fall foliage.

Things to Do in St. Louis
1
Gateway Arch
The iconic symbol of St. Louis. Take the tram to the top for views.
2
Forest Park
Home to the zoo and art museum. It is larger than Central Park.
3
City Museum
An interactive playground for all ages built from reclaimed materials.
4
Anheuser-Busch Brewery
Take a historic tour of the facility and learn about brewing traditions.
Tags
Eden Prairie to St. Louis drive I-35 to I-70 route Minnesota to Missouri road trip St. Louis travel guide driving to St. Louis best route from Minneapolis to St. Louis road trip tips Midwest travel