The distance from Eugene to Houston is over 2,300 miles, making flying the only practical mode of transport. You can fly from Eugene Airport (EUG) to George Bush Intercontinental (IAH) with a connection in a major hub like Denver, Phoenix, or Seattle. The flight time typically ranges from 7 to 9 hours depending on the layover. Driving is possible but would take several days, making it less efficient for most travelers.
Total Distance: 3,700 km driving, 3,000 km air distance.
United Airlines has a major hub in Houston, offering good connectivity.
October to April for mild weather.