The most practical way to travel from Fairbanks, Alaska to Chicago, Illinois is by air. Flights from Fairbanks International Airport (FAI) to O'Hare International Airport (ORD) typically require a connection in Seattle. The total travel time is usually 8 to 10 hours. Driving is not a practical option for this distance.
Total Distance: 5,800 km driving, 4,200 km air.
United and Alaska Airlines offer the most reliable connections.
May to September for pleasant weather in Chicago.