Is there a train to Key West?

There is no train service to Key West; you must drive or fly.

How long is the drive?

It takes about 26 hours of driving time.

What is the best time to visit?

Winter is the most pleasant time for weather.

There are some toll roads in the Florida area.

Like any major city, stay in tourist-friendly areas and remain vigilant.

Ferndale

Key West

Driving

Ferndale to Key West

Updated: 28 May 2026

The drive from Ferndale to Key West covers approximately 1,600 miles. The most efficient route follows I-75 South to US-1 South. This drive typically takes 26 hours of active driving time. You will pass through several states, including Ohio, Kentucky, Tennessee, Georgia, and Florida.

Total Distance: 2,600 km driving, 2,100 km air distance.

Fastest Way

Driving is the fastest, taking 26 hours of active driving time.

Cheapest Way

Driving is the most cost-effective for this long-distance trip.

Compare Ferndale to Key West Routes

Driving

Direct

Duration

26 hours

Avg Price

$300-$400 in fuel

Operator

Personal Vehicle

Route

I-75 South to US-1 South.

Plan at least two overnight stops to break up the long drive.

Travel Tips

Overnight Stops
Book hotels in advance if traveling during peak tourist seasons.
Traffic
Expect significant traffic delays in Atlanta and Miami.
Parking
Parking in Key West is expensive; use hotel parking or public garages.
Weather
Key West is very hot and humid in the summer; plan indoor activities for the afternoon.
Safety
Stay in well-populated areas and avoid walking alone at night.

Safety Tips

Fatigue
Do not attempt to drive the entire 26 hours in one sitting; prioritize rest.
Vehicle Prep
Check your tires and cooling system before leaving, as the southern heat is intense.
Emergency
Keep a roadside assistance plan active for the duration of the trip.
Awareness
Be cautious of scams in tourist-heavy areas like Duval Street.