Is Des Moines worth visiting?

Yes, it offers a vibrant downtown and cultural attractions.

How long is the drive?

The drive is approximately 6 hours.

No, this route does not have toll roads.

What is the best time to leave?

Early morning is best to avoid traffic.

Is it a scenic drive?

It features rolling hills and farmland scenery.

Festus

Des Moines

Driving

Festus to Des Moines

Updated: 30 May 2026

Traveling from Festus to Des Moines covers roughly 400 miles of Midwestern landscape. You will head north through Missouri, typically connecting to I-35 North near Kansas City or via US-61 depending on your preference. The journey takes about 6 hours of pure driving time. You will pass through diverse agricultural regions and small towns. It is a popular route for those heading into the heart of Iowa.

Total Distance: 645 km driving, 580 km air distance.

Fastest Way

Driving is the fastest method, taking 6 hours.

Cheapest Way

Driving is the most economical choice, costing roughly 60 dollars in fuel.

Compare Festus to Des Moines Routes

Driving

Direct

Duration

6 hours

Avg Price

50-70 USD

Operator

Personal Vehicle

Route

I-55 N to I-70 W to I-35 N.

Use cruise control to maintain steady speeds on the flat Iowa stretches.

Travel Tips

Road Construction
Check for seasonal road work on I-35 before departing.
Dining
Stop in Des Moines for excellent farm-to-table dining options.
Parking
Downtown Des Moines has ample parking garages for visitors.
Weather
Be prepared for sudden weather changes in the Midwest.
Hydration
Keep water in the car for long stretches between major towns.

Safety Tips

Winter Driving
Avoid travel during heavy snowstorms as I-35 can become icy.
Lights
Ensure your headlights are functional for early morning or late evening driving.
Alertness
Switch drivers if possible to avoid fatigue on the 6-hour trip.
Emergency Contact
Keep a list of local emergency numbers for Missouri and Iowa.