The trip from Folly Beach to Greenville spans 340 kilometers, moving from the coast to the foothills of the Blue Ridge Mountains. You will take I-26 West for the majority of the journey before merging onto I-385 North. The drive typically takes 3.5 hours. This route showcases the diverse geography of South Carolina, from sea level to the rolling hills of the Upstate.
Total Distance: 340 km driving distance; 310 km straight-line air distance.
The stretch of I-26 near Columbia can be confusing; follow signs for Greenville carefully.
October is perfect for visiting, as the fall foliage in the nearby mountains is spectacular.