Gainesville
Gainesville
Little Rock
Little Rock
Driving

Gainesville to Little Rock

Updated: 28 May 2026

The drive from Gainesville to Little Rock covers approximately 250 kilometers. You will head south on MO-5, then transition to US-65 South, which leads directly into Little Rock. The trip takes about 3 hours. Driving is the most practical mode of transport, as there is no direct public transit available from Gainesville.

Total Distance: 250 km driving, 210 km air distance.
Fastest Way
Driving via MO-5 and US-65 is the fastest route, taking 3 hours.
Cheapest Way
Driving your own vehicle is the most economical way to travel.
Compare Gainesville to Little Rock Routes
Driving
Direct
Duration
3 hours
Avg Price
$25-$40 in fuel
Operator
Personal Vehicle
Route
Take MO-5 South to US-65 South into Little Rock.

US-65 is a scenic highway; watch for winding sections.

Travel Tips
  • Traffic
    Little Rock traffic is generally light, but avoid rush hours.
  • Navigation
    Use a GPS to navigate the city streets.
  • Dining
    Try the local Southern cuisine.
  • Parking
    Downtown parking is available in garages.
  • Safety
    Be aware of your surroundings in urban areas.
Safety Tips
  • Speed
    Watch for speed limit changes on US-65.
  • Weather
    Arkansas is prone to severe weather; monitor forecasts.
  • Vehicle
    Check your tires and fluids before the drive.
  • Visibility
    Use headlights during rain or low light.
People Also Ask
  • Is there a train?
    No, there is no train service from Gainesville to Little Rock.
  • How long is the drive?
    The drive takes approximately 3 hours.
  • What is the best route?
    MO-5 South to US-65 South is the standard route.
  • Are there tolls?
    No, there are no toll roads on this route.
  • Is it a safe drive?
    Yes, US-65 is a well-maintained highway.
Quick Info
  • From Gainesville, Missouri, United States
  • To Little Rock, Arkansas, United States
  • Modes
Best Time to Travel

Spring and Fall are ideal for enjoying the city's parks and outdoor attractions.

Things to Do in Little Rock
1
Clinton Library
Visit the presidential library and museum.
2
River Market
Explore the shops, restaurants, and farmers market.
3
Pinnacle Mountain
Hike the trails at this state park.
4
Old State House
Tour the historic capitol building.
Tags
Gainesville to Little Rock MO-5 South US-65 South driving to Little Rock Missouri to Arkansas Gainesville MO Little Rock AR guide road trip