New Orleans is a historic city located east of Galveston. The drive is approximately 550 kilometers and takes about 6 hours via I-10. This is a popular route for weekend trips. You will cross the Galveston Causeway to leave the island.
Total Distance: 550 km driving; 450 km air distance.
The route is straightforward and well-marked.
Weekdays mid-morning to avoid heavy rush hour traffic.