The drive from Garner to Charleston, South Carolina, covers roughly 280 miles and takes about 4.5 hours. You will primarily travel south on I-95 before transitioning to I-26 East toward the coast. This route takes you through the heart of the Lowcountry, offering a transition from the Piedmont to the Atlantic shoreline. Be prepared for heavy traffic near the South Carolina border during holiday weekends.
Total Distance: 450 km driving distance; 380 km straight-line air distance.
Stop in Florence, SC, for a quick break and fuel.
Spring or Fall for mild weather, perfect for walking the historic district.