Is there a train to St. Louis?

No, there is no practical train service from West Virginia.

What is the best highway?

I-64 West is the primary route.

Yes, it is a standard interstate drive.

Glen Ferris

St. Louis

Driving

Glen Ferris to St. Louis

Updated: 30 May 2026

The drive from Glen Ferris to St. Louis is approximately 600 miles, primarily following I-64 West. This route takes you through Kentucky and southern Illinois before arriving in Missouri. The journey takes about 9 hours of driving time. It is a straightforward interstate drive, making it a practical option for those who prefer to drive rather than fly.

Total Distance: 965 km driving distance; 850 km straight-line air distance.

Fastest Way

Driving via I-64 is the fastest method, taking approximately 9 hours.

Cheapest Way

Driving is the most cost-effective way to reach St. Louis.

Compare Glen Ferris to St. Louis Routes

Driving

Direct

Duration

9 hours

Avg Price

100-150 USD

Operator

Personal Vehicle

Route

I-64 W.

Plan for a stop in Louisville or Evansville to break up the drive.

Travel Tips

Traffic
Avoid the downtown St. Louis area during morning and evening rush hours.
Parking
Use the parking garages near the Arch or Forest Park for easy access.
Dining
Try the local St. Louis-style pizza and toasted ravioli.
Navigation
I-64 is well-marked, but keep an eye on GPS for construction updates.
Rest Stops
There are plenty of service stations along I-64 in Kentucky and Illinois.

Safety Tips

Interstate Driving
Stay alert on I-64, as traffic can be heavy near major cities.
Weather
Be prepared for sudden thunderstorms in the Midwest during the summer.
Vehicle Check
Ensure your vehicle is in good condition for a long-distance drive.
Emergency
Keep a basic emergency kit in your car for long-distance travel.