Glendale
Glendale
Des Moines
Des Moines
Flight Driving

Glendale to Des Moines

Updated: 28 May 2026

The journey from Glendale to Des Moines covers over 1,400 miles. Flying from Phoenix Sky Harbor to Des Moines International Airport is the most efficient choice, taking about 3.5 hours. Driving is a long trip, taking approximately 18 hours via Interstate 17 and Interstate 80. This route takes you through the desert and into the heart of the Midwest. Be prepared for varying landscapes and weather conditions.

Total Distance: 2,300 km driving distance; 1,800 km straight-line air distance.
Fastest Way
Flying is the fastest method, saving you over 14 hours of travel time.
Cheapest Way
Flying is generally more economical than the cost of fuel and multiple hotel nights for a long drive.
Compare Glendale to Des Moines Routes
Flight
Direct
Driving
Direct
Duration 3 hours 30 minutes 18 hours
Avg Price $250-$500 $220-$280 in fuel
Operator American Airlines Personal Vehicle
Route PHX to DSM. I-17 North to I-80 East.
Tip The airport is located about 15 minutes from downtown Des Moines. Plan for an overnight stop in Denver or Omaha.
Travel Tips
  • Weather
    Des Moines weather can be unpredictable; check local reports before heading out.
  • Dining
    Try the local farm-to-table restaurants; Iowa is famous for its fresh produce.
  • Transportation
    A car is recommended for exploring the city and surrounding areas.
  • Outdoor Activities
    Des Moines has many parks and trails; take advantage of the city's outdoor lifestyle.
  • Airport Transit
    The airport is well-connected to the city via rideshares and taxi services.
Safety Tips
  • Highway Safety
    I-80 is a major route; stay alert and maintain a safe distance from other vehicles.
  • Emergency Preparedness
    Carry a roadside emergency kit if driving, as the route can be remote.
  • Urban Safety
    Be aware of your surroundings in downtown areas at night and use rideshares for late-night travel.
  • Weather Alerts
    Iowa is prone to severe weather; keep an eye on local reports during your stay.
People Also Ask
  • Is Des Moines a good city for tourists?
    Yes, it offers a wide range of cultural, scientific, and culinary attractions.
  • How long is the flight?
    The flight time is approximately 3.5 hours.
  • Are there direct flights?
    Yes, American Airlines offers frequent direct flights from PHX to DSM.
  • What is the best time to visit?
    Late spring to early fall offer the most comfortable weather for exploring.
  • Do I need a car in Des Moines?
    A car is highly recommended, as the city is spread out.
Quick Info
  • From Glendale, Arizona, United States
  • To Des Moines, Iowa, United States
  • Modes
Best Time to Travel

Late spring to early fall for pleasant weather, as Des Moines winters are cold.

Things to Do in Des Moines
1
Iowa State Capitol
A beautiful historic building with a gold-leaf dome. It offers free tours.
2
Greater Des Moines Botanical Garden
A stunning garden with a geodesic dome and various themed areas.
3
Des Moines Art Center
A world-class art museum featuring a diverse collection of modern and contemporary art.
4
East Village
A vibrant neighborhood with shops, restaurants, and historic buildings.
Tags
Glendale to Des Moines PHX to DSM flights driving to Des Moines I-80 route traveling to Iowa best way to reach Des Moines Arizona to Midwest Des Moines travel guide