Is there a bus route?

Bus travel is possible but involves multiple transfers and takes significantly longer than driving.

What is the best time to leave?

Leaving early in the morning helps you avoid traffic in Denver.

Are there hotels on the way?

Yes, there are numerous hotels in cities like North Platte and Kearney along I-80.

Is Des Moines walkable?

The downtown area is quite walkable, but a car is recommended for exploring the suburbs.

There is no direct Amtrak service to Des Moines.

Grand Junction

Des Moines

Flight Driving

Grand Junction to Des Moines

Updated: 28 May 2026

Traveling from Grand Junction to Des Moines covers approximately 1,400 kilometers across the American West and Midwest. The most direct route follows I-70 East to I-80 East, passing through Denver, Cheyenne, and Omaha. Flying is a viable alternative, usually requiring a connection through a major hub like Denver or Chicago. The landscape transitions from the rugged Rocky Mountains to the rolling cornfields of Iowa. This route is a classic cross-country trek that requires careful planning for fuel and rest stops.

Total Distance: 1,400 km driving distance; 1,180 km straight-line air distance.

Fastest Way

Flying is the fastest option, saving nearly 8 hours compared to driving.

Cheapest Way

Driving is the most economical choice for travelers with multiple passengers.

Compare Grand Junction to Des Moines Routes

	Flight Connecting	Driving Direct
Duration	6 hours	14 hours
Avg Price	$450-$800	$200-$300 in fuel
Operator	American Airlines	Personal Vehicle
Route	GJT to ORD or DEN to DSM.	I-70 East to I-80 East.
Tip	Check flights into Des Moines International Airport (DSM) for the best availability.	Plan for an overnight stop in Omaha to break up the long drive.

Travel Tips

Rest Stops
Utilize the well-maintained rest areas along I-80 in Nebraska and Iowa.
Speed Limits
Adhere strictly to speed limits, especially in small towns along the interstate.
Weather Alerts
Monitor local news for thunderstorm warnings during the spring and summer months.
Vehicle Check
Ensure your tires and fluids are checked before embarking on this long-distance journey.
Snacks
Pack a cooler with water and snacks to minimize stops in rural areas.

Safety Tips

Night Driving
Avoid driving late at night to reduce the risk of hitting wildlife on rural stretches.
Towing
If towing a trailer, ensure your vehicle is rated for mountain passes in Colorado.
Communication
Carry a portable power bank to keep your phone charged for navigation.
Roadside Assistance
Have a membership for roadside assistance in case of mechanical issues.