Driving
Greenwood to Pittsburgh
Updated: 28 May 2026
The drive from Greenwood to Pittsburgh covers approximately 950 miles, taking you through the heart of the South and into the industrial Northeast. You will primarily use I-65 N and I-70 E, passing through Nashville and Columbus. The trip takes about 15 hours of driving time. Pittsburgh is known for its three rivers and rich steel history. Prepare for mountainous terrain as you approach Pennsylvania.
Total Distance: 1528 km driving, 1300 km air distance.
Fastest Way
Driving is the most practical method for this route.
Cheapest Way
Driving is the most cost-effective way to reach Pittsburgh.
Compare Greenwood to Pittsburgh Routes
Driving
Direct
Duration
15 hours
Avg Price
$160-$220 in fuel
Operator
Personal Vehicle
Route
I-65 N, I-71 N, I-70 E.
Stop in Nashville for a break and some live music.
Travel Tips
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Mountain DrivingUse lower gears when descending steep grades in PA.
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TrafficAvoid downtown Pittsburgh during rush hour.
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DiningTry a Primanti Bros. sandwich while in the city.
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ParkingUse public transit or parking garages in the city center.
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WeatherBe prepared for rain in the Ohio Valley.
Safety Tips
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Road ConditionsCheck for construction on I-70 in Ohio.
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FatigueTake frequent breaks in Nashville and Columbus.
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Vehicle PrepCheck your brakes before driving in the mountains.
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Emergency KitCarry a flashlight and basic tools.
People Also Ask
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Is it a scenic drive?Yes, the Appalachian mountains are beautiful.
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Are there tolls?Yes, some sections of the Pennsylvania Turnpike have tolls.
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How long is the drive?It takes about 15 hours of driving time.
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What is the best route?I-65 N to I-70 E is the most direct path.
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Is Pittsburgh safe?It is generally safe, but standard urban precautions apply.
Quick Info
- From Greenwood, Mississippi, United States
- To Pittsburgh, Pennsylvania, United States
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Modes
Best Time to Travel
Autumn for the stunning fall foliage in the mountains.
Things to Do in Pittsburgh
1
The Duquesne Incline
Ride the historic funicular for a breathtaking view of the city skyline and rivers.
2
Carnegie Museum of Natural History
Explore one of the best dinosaur collections in the world. It is a must-see for families.
3
Point State Park
Visit the confluence of the three rivers. It is a beautiful spot for a walk.
4
Andy Warhol Museum
Discover the life and work of the famous pop artist in his hometown.
Tags
Greenwood to Pittsburgh
driving to Pittsburgh
MS to PA road trip
Greenwood to PA
best route to Pittsburgh
long distance driving
Pittsburgh travel guide
traveling north from MS
