The drive from Greenwood to St. Louis covers 400 miles and takes about 6 hours via I-55 North. You will travel through the heart of Mississippi, Tennessee, and into Missouri. This route is a major corridor connecting the Delta to the gateway city of St. Louis. A personal vehicle is the most practical mode of transport for this trip.
Total Distance: 640 km driving distance; 550 km straight-line air distance.
I-55 is a major interstate with frequent service stations.
October for the pleasant weather and outdoor festivals.