Is it better to drive or fly?

Driving is a great way to see the country, but flying is much faster.

How long is the drive?

Expect about 13 to 14 hours of driving time.

Are there direct flights?

No, you will likely have a connection.

What is the best time to visit?

Spring and fall are ideal for weather and events.

Greyhound offers service, but it takes significantly longer than driving.

Hampton

St. Louis

Flight Driving

Hampton to St. Louis

Updated: 28 May 2026

The distance from Hampton to St. Louis is approximately 1,300 kilometers. Driving is a very practical choice, typically taking about 13 to 14 hours via I-64 and I-70. You will pass through the scenic Appalachian Mountains and the heart of the Midwest. Flying from Norfolk (ORF) to St. Louis Lambert International Airport (STL) is also available, usually requiring a connection. This route takes you from the Atlantic coast to the banks of the Mississippi River.

Total Distance: 1,300 km driving, 1,100 km air distance.

Fastest Way

Flight from Norfolk (ORF) to St. Louis (STL) takes about 5 hours including layovers.

Cheapest Way

Driving is the most cost-effective for this distance.

Compare Hampton to St. Louis Routes

	Flight Connecting	Driving Direct
Duration	5 hours	13 hours
Avg Price	$250-$500	$200-$350
Operator	American Airlines	Personal Vehicle
Route	ORF to STL via CLT or ORD.	I-64 W to I-70 W.
Tip	American Airlines offers frequent connections for this route.	The drive is straightforward and scenic.

Travel Tips

Cuisine
Try the local food scene, especially the St. Louis-style pizza and toasted ravioli.
Transportation
St. Louis is a large city; renting a car is highly recommended.
Parking
Parking is generally available, but check for fees in downtown areas.
Weather
Be prepared for cold winters and mild summers.
Booking
Book your hotel in advance, especially if visiting for major events.