The trip from Hancock to Birmingham is a 750-mile journey. You will head south on I-81 and then south on I-65. This route takes you through the beautiful Appalachian Mountains and across the South. It is a scenic drive with plenty of history along the way.
Total Distance: 1,200 km driving, 1,000 km air.
Stop in Knoxville for a break.
Spring or Fall for mild weather.