The journey from Harpers Ferry to Charleston, South Carolina, covers about 900 kilometers. The most practical way is to drive to Washington Dulles (IAD) and take a flight to Charleston International Airport (CHS). Charleston is famous for its historic architecture and coastal charm. This route connects the Appalachian region to the Southern coast.
Total Distance: 900 km driving distance; 750 km straight-line air distance.
Direct flights are available and highly recommended.
Spring and Fall offer the most comfortable weather for sightseeing.