Hollister
Hollister
Birmingham
Birmingham
Driving

Hollister to Birmingham

Updated: 28 May 2026

The journey from Hollister to Birmingham covers approximately 550 miles southeast through Missouri, Arkansas, and Mississippi. Driving via US-65 and I-22 is the most direct route, taking about 9 hours. Birmingham is famous for its civil rights history and its industrial heritage.

Total Distance: 880 km driving, 750 km air distance.
Fastest Way
Driving takes about 9 hours of pure transit time.
Cheapest Way
Driving is the most economical and practical way to reach Birmingham from Hollister.
Compare Hollister to Birmingham Routes
Driving
Direct
Duration
9 hours
Avg Price
$100-$140 in fuel
Operator
Personal Vehicle
Route
US-65 S to I-40 E, then I-22 E through Memphis.

Plan your departure to avoid Memphis rush hour traffic.

Travel Tips
  • Traffic
    Be prepared for traffic in Memphis and when entering Birmingham.
  • Parking
    Use parking garages downtown; street parking is limited.
  • Walking
    The downtown area is walkable, especially in the Civil Rights District.
  • Weather
    Alabama summers can be very hot and humid; check the forecast before you leave.
  • Local Food
    Try the famous Southern barbecue at a local restaurant.
Safety Tips
  • Highway Safety
    Stay alert on I-22, as it can have heavy truck traffic.
  • Urban Safety
    Stick to well-lit areas when walking downtown at night.
  • Vehicle Prep
    Ensure your car is in good condition for a 9-hour drive.
  • Emergency Prep
    Keep a basic emergency kit in your car.
People Also Ask
  • Is there a direct flight?
    No, there are no direct flights from Springfield to Birmingham.
  • How long is the drive?
    The drive takes about 9 hours of pure driving time.
  • What is the best route?
    Taking I-40 to I-22 is the most direct route.
  • Are there tolls?
    The route is generally toll-free.
  • Is Birmingham safe?
    The city is generally safe, but standard urban precautions apply.
Quick Info
  • From Hollister, Missouri, United States
  • To Birmingham, Alabama, United States
  • Modes
Best Time to Travel

April to May or September to October for pleasant weather.

Things to Do in Birmingham
1
Birmingham Civil Rights Institute
Learn about the history of the Civil Rights Movement in this powerful museum.
2
Barber Vintage Motorsports Museum
Visit this world-class museum featuring a massive collection of motorcycles.
3
Sloss Furnaces National Historic Landmark
Explore the historic iron-making facility.
4
Birmingham Museum of Art
Visit one of the largest regional art museums in the Southeast.
Tags
Hollister to Birmingham travel driving Missouri to Alabama best route Hollister to Birmingham travel tips Missouri to Alabama Birmingham travel guide Hollister transport Southern road trip