The journey from Horse Cave to San Diego is a long-distance trip of approximately 2,100 miles. You will head south to Nashville, then take I-40 West all the way to Barstow, before connecting to I-15 South into San Diego. This route takes you through the heart of the American Southwest, including the deserts of Arizona and California. Expect a total drive time of 32 hours or more. Plan for multiple overnight stops.
Total Distance: 3,380 km driving distance; 2,800 km straight-line air distance.
Carry extra water for the desert stretches.
Spring or autumn to avoid extreme desert heat in summer.