Hudson
Hudson
St. Louis
St. Louis
Driving

Hudson to St. Louis

Updated: 28 May 2026

The journey from Hudson to St. Louis is approximately 600 miles. The most direct route is via I-71 South to I-70 West. Expect a drive time of about 9 hours without major stops. You will pass through Indianapolis on your way to Missouri. This is a long-haul drive that requires careful planning.

Total Distance: 965 km driving, 850 km air distance.
Fastest Way
Driving via I-70 is the fastest, taking 9 hours.
Cheapest Way
Driving is the most practical and cheapest option for this distance.
Compare Hudson to St. Louis Routes
Driving
Direct
Duration
9 hours
Avg Price
$120-$150 in fuel
Operator
Personal Vehicle
Route
I-71 S to I-70 W

Plan for at least two major stops to stretch your legs.

Travel Tips
  • Stops
    Indianapolis is a great halfway point for lunch.
  • Traffic
    Avoid the I-70 corridor through downtown St. Louis during rush hour.
  • Accommodation
    Book hotels with parking included to save money.
  • Navigation
    Download offline maps as cell service can be spotty in rural areas.
  • Hydration
    Keep plenty of water in the car for the long drive.
Safety Tips
  • Fatigue
    Switch drivers if possible to avoid drowsy driving.
  • Weather
    Check for severe weather alerts in the Midwest plains.
  • Vehicle Check
    Check tire pressure before leaving for this long trip.
  • Emergency
    Keep a charged power bank for your phone.
People Also Ask
  • Is it a safe drive?
    Yes, it is a standard interstate route.
  • How long does it take?
    Approximately 9 hours of driving time.
  • Are there tolls?
    Most of this route is toll-free.
  • Is flying better?
    Flying is faster but requires airport transit time.
  • What is the best route?
    I-71 to I-70 is the most direct path.
Quick Info
  • From Hudson, Ohio, United States
  • To St. Louis, Missouri, United States
  • Modes
Best Time to Travel

Spring or fall for comfortable temperatures in the Gateway City.

Things to Do in St. Louis
1
Gateway Arch
Visit the iconic monument to westward expansion. You can take a tram to the top.
2
Forest Park
Explore this massive urban park, which is larger than Central Park in New York.
3
City Museum
Experience an interactive playground built from repurposed industrial objects.
4
St. Louis Zoo
Enjoy free admission to one of the top-rated zoos in the country.
Tags
Hudson to St. Louis driving to St. Louis I-70 route Ohio to Missouri drive St. Louis travel guide fastest way to St. Louis road trip to Missouri Hudson to St. Louis distance midwest road trip traveling to St. Louis