Is there a bus to Louisville?

No, there is no direct public bus service from Huntington.

How long is the drive?

It takes about 3 hours and 30 minutes.

What is the best route?

Taking I-69 South to I-65 South is the standard route.

Yes, there are tolls on the bridges crossing the Ohio River.

Yes, it is a standard highway drive.

Huntington

Louisville

Driving

Huntington to Louisville

Updated: 28 May 2026

The drive from Huntington to Louisville is approximately 200 miles and takes about 3 hours and 30 minutes. You will head south on I-69 and then transition to I-65 South toward Louisville. This route takes you through the heart of Indiana. Louisville is a historic city on the Ohio River, famous for the Kentucky Derby. There is no direct public transit between these two cities.

Total Distance: 320 km driving distance; 280 km straight-line air distance.

Fastest Way

Driving via I-69 and I-65 is the fastest route, typically taking 3 hours and 30 minutes.

Cheapest Way

Driving your own vehicle is the most cost-effective way to reach Louisville.

Compare Huntington to Louisville Routes

Driving

Direct

Duration

3 hours 30 mins

Avg Price

$45-$55 in fuel

Operator

Personal Vehicle

Route

I-69 South to I-65 South

Traffic can be heavy entering Louisville; plan your arrival accordingly.

Travel Tips

Parking
Use the parking garages downtown for easy access to attractions.
Dining
Explore the restaurants in the NuLu neighborhood.
Navigation
Louisville's highway system can be complex; keep your GPS active.
Events
Check the schedule for events at the KFC Yum! Center.
Walking
The Waterfront Park is a great place for a walk with views of the river.