The drive from Huntsville to Little Rock is a 500 km journey. You will primarily use I-65 N and I-40 W, which takes you through Memphis. The trip typically takes 5 to 6 hours depending on traffic. This route is popular for those visiting the Ozarks or the Arkansas capital. Ensure your vehicle is ready for the drive through the Mississippi River valley.
Total Distance: 500 km driving, 450 km air distance.
Stop in Memphis for lunch to break up the drive.
Spring and Autumn for mild weather.